A Simple High Performance Thin Layer Chromatography Method For The Simulateneous Estimation Of Aspirin And Rosuvastatin calcuim In Bulk Drug And Marketed Formulation Is Developed.The Determination Was Carried On Silica Gel 60 GF254 HPTLC Plates Using A Mobile Phase Of Ethyl Acetate:Toluene:Acetone:Glacial Acetic Acid(4:4:2:0.1). The Absorbance Of The Spots Was Measured By Densitometry At 254 Nm.The Retention Factor (Rf) For Rosuvastatin calcuim Was 0.36, And For Aspirin 0.60. Aspirin And Rosuvastatin calcium Showed A Linear Response In The Concentrarion Range 300ng-750ng And 40ng-100ng/Band Respectively. The Correlation Co-Efficient (R2 Value) For Aspirin And Rosuvastatin calcuim Was 0.9965 And 0.9992 For Both Grug.The Result Of Analysis Have Been Validated Statistically And By Recovery Studies. The Percentage Recoveries Obtained For Aspirin And Rosuvastatin calcuim Ranges From 99.100 To 101.94.
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